Recombinant Mouse TRAF-interacting protein with FHA domain-containing protein B (Tifab)

中文名稱：

小鼠Tifab重組蛋白
貨號：

CSB-YP812949MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Tifab重組蛋白
貨號：

CSB-EP812949MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Tifab重組蛋白
貨號：

CSB-EP812949MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tifab重組蛋白
貨號：

CSB-BP812949MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tifab重組蛋白
貨號：

CSB-MP812949MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tifab
Uniprot No.：

Q8JZM6
別名：

Tifab; TRAF-interacting protein with FHA domain-containing protein B; TIFA-like protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-147
氨基酸序列

MERPLTVLQV SLYHPTQGPV AFAHVPQQLQ HDASRLLVGR GQNTHLQLQL PQLSRYHLSL EPYLEKGSSL LAFCLKVLTR KSCVWVNGLP LRYLEQVPLG TINRISFSGI QMLVRKEGGA SLETFVCYFH LSPSPLIYRP KAQETDE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA.
基因功能參考文獻：
1. Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms PMID: 26944478
2. TIFAB loss increases TRAF6 protein and the dynamic range of TLR4 signaling PMID: 26458771
3. study shows TIFAB is mainly expressed in B cells rather than T cells in the spleen; results suggest TIFAB could act as a negative regulator of TRAF6-induced cellular function such as B cell proliferation and maturation of dendritic cellss & macrophages PMID: 19470519
組織特異性：

Expressed at high levels in spleen and at moderate levels in lung, thymus, and small intestine.
數據庫鏈接：

KEGG: mmu:212937

UniGene: Mm.116697