Recombinant Mouse Serologically defined colon cancer antigen 8 homolog (Sdccag8)

中文名稱：

小鼠Sdccag8重組蛋白
貨號：

CSB-YP770462MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Sdccag8重組蛋白
貨號：

CSB-EP770462MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Sdccag8重組蛋白
貨號：

CSB-EP770462MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Sdccag8重組蛋白
貨號：

CSB-BP770462MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Sdccag8重組蛋白
貨號：

CSB-MP770462MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sdccag8
Uniprot No.：

Q80UF4
別名：

Sdccag8; Cccap; Serologically defined colon cancer antigen 8 homolog; Centrosomal colon cancer autoantigen protein; mCCCAP
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-717
氨基酸序列

MAKSPGNSTL EDSLGQYQRS LRERANRSIH QLKCALREVD VTVEEDALDP STSINVENED TGVAWHELQH SHAVNQLKAL LRQQTNKENE TSPPRRRKLS PSRPSECDDG SMPTMHNLVP IINDQSQYIH HLEAEVKFCK DELSGMKNRV QVVVLENERL QQELKSQRPE ETLREQTFLD ASGNMQNSWI MTREDSRVDE AAKRPFSHGD AETGKTASTG DANKWKLELE RLKLTYEAKT DLLESQLMLL RKDLAEYQKT CEDLKERLKH KESLLAASAS SRVGGLCLKC AQHEAVLSQT HSNVHIQTIE RLTKERDDLM SVLVSVRSSL AEAQKRETSA YEQVKHAVQM TEEANFEKTK ALIQCEQLKS ELERQTERLE KELASQQEKR AVEKEMIKKE VAREREDAES KMLILSQNIA KLEAQVEKVT REKTAAVSHL EEIQNHVASQ EMDVTKVCGE MRFQLNKTKM EKDEVEKEHR EYKAKSHKDL EMKVQEIEKL RLELSESEQH VEQEQQKAAR ARQECLRVTE LLGEAERQLH LTRLEKDSIQ QSFSNEAKAQ ALQAQQREQE LTQKIQQMET QHDKTESEQY LLLTSQNTFL TKLKEECCLL AKKLEKVSLK SRSQIVRLSQ EKRYLCDKLE KLQKRNDELE EQCIQHGRVH ETMKERLRQL DKHGQATAQQ LVQLLNKQNQ LLLERQNLSE EVARLRAQLP SMPQSDC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in the establishment of cell polarity and epithelial lumen formation. Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
基因功能參考文獻：
1. ascribe the patterning defects in the limb and the secondary palate as well as lung abnormalities to loss of SDCCAG8, while the developmental defects in the brain are likely due to the loss of AKT3 PMID: 29444170
2. Our analysis of Sdccag8(gt/gt) mice indicates that the pleiotropic phenotypes in these mice may arise through multiple tissue-specific disease mechanisms. PMID: 24722439
3. results reveal a critical role for SDCCAG8 in controlling centrosomal properties and function. PMID: 25088364
亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell junction.
組織特異性：

Expressed in liver, kidney, spleen, brain, heart and muscle. Expressed in photoreceptor cells of the retina.
數據庫鏈接：

KEGG: mmu:76816

STRING: 10090.ENSMUSP00000027785

UniGene: Mm.171399