Recombinant Mouse Rho-related GTP-binding protein RhoN (Rnd2)

中文名稱(chēng)：

小鼠Rnd2重組蛋白
貨號(hào)：

CSB-YP874129MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

小鼠Rnd2重組蛋白
貨號(hào)：

CSB-EP874129MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

小鼠Rnd2重組蛋白
貨號(hào)：

CSB-EP874129MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

小鼠Rnd2重組蛋白
貨號(hào)：

CSB-BP874129MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

小鼠Rnd2重組蛋白
貨號(hào)：

CSB-MP874129MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rnd2
Uniprot No.：

Q9QYM5
別名：

Rnd2; Arhn; Rho7; Rhon; Rho-related GTP-binding protein RhoN; Rho family GTPase 2; Rho-related GTP-binding protein Rho7; Rnd2
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-224
氨基酸序列

MEGQSGRCKI VVVGDAECGK TALLQVFAKD AYPGSYVPTV FENYTASFEI DKRRIELNMW DTSGSSYYDN VRPLAYPDSD AVLICFDISR PETLDSVLKK WQGETQEFCP NAKVVLVGCK LDMRTDLATL RELSKQRLIP VTHEQGTVLA KQVGAVSYVE CSSRSSERSV RDVFHVATVA SLGRGHRQLR RTDSRRGLQR STQLSGRPDR GNEGEMHKDR AKSC
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.
基因功能參考文獻(xiàn)：
1. RP58 represses transcription of Rnd2 via binding to a 3'-regulatory enhancer in a sequence-specific fashion. Using reporter assays, we found that RP58 repression of Rnd2 is competed by proneural basic helix-loop-helix transcriptional activators. PMID: 24084125
2. Data demonstrate that COUP-TFI modulates late-born neuron migration and favours proper differentiation of callosal projection neurons by finely regulating Rnd2 expression levels. PMID: 21965613
3. results identify Rnd2 as a novel essential regulator of neuronal migration in the cerebral cortex and demonstrate that Rnd2 is a major effector of Neurog2 function in the promotion of migration PMID: 18690213
4. Rnd2 bound to Plexin-D1 in cortical neurons, and Sema3E/Plexin-D1-induced inhibition of axon outgrowth of cortical neurons required Rnd2 and down-regulation of R-Ras activity. PMID: 19136556
亞細(xì)胞定位：

Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rho family
組織特異性：

Expressed specifically in neurons in the brain and spinal cord and also in hepatic stellate cells.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:11858

STRING: 10090.ENSMUSP00000001347

UniGene: Mm.378883