Recombinant Mouse Protein diaphanous homolog 2 (Diaph2), partial

中文名稱：

小鼠Diaph2重組蛋白
貨號：

CSB-YP006891MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Diaph2重組蛋白
貨號：

CSB-EP006891MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Diaph2重組蛋白
貨號：

CSB-EP006891MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Diaph2重組蛋白
貨號：

CSB-BP006891MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Diaph2重組蛋白
貨號：

CSB-MP006891MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Diaph2
Uniprot No.：

O70566
別名：

Diaph2; Diap2Protein diaphanous homolog 2; Diaphanous-related formin-2; DRF2; mDia3
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in oogenesis.
基因功能參考文獻：
1. mDia induces circumferential actin filaments around the edge of the synaptic cleft, which contract the presynaptic terminals in a ROCK-dependent manner. PMID: 27880913
2. These results imply that RhoD activated by FGF signaling forms cytoneme-like protrusions through activation of mDia3C, which induces actin filament formation PMID: 23034183
3. study examined how mDia functions in axon guidance in vivo and in vitro; findings show mDia plays multiple roles in the proper formation of the neural network PMID: 23890216
4. actin cytoskeleton regulated by Rho-mDia pathway is critical for the integrity of the adherens junctions and the polarity of neuroepithelial cells PMID: 21980468
5. Cdc42, and its effector, mDia3, regulate microtubule attachment to kinetochores PMID: 15085137
6. These results indicate that RhoA-dependent signaling through mDia1/2 and the MRTFs is important for SMC-specific gene expression in smooth muscle cells. PMID: 17170370
7. analysis of interactions between mDia isoforms 1, 2, and 3 and RhoA, Rac1, and Cdc42 PMID: 18829452
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蛋白家族：

Formin homology family, Diaphanous subfamily
數據庫鏈接：

STRING: 10090.ENSMUSP00000039334

UniGene: Mm.10763