Recombinant Mouse Protein SCO2 homolog, mitochondrial (Sco2), partial

中文名稱：

小鼠Sco2重組蛋白
貨號：

CSB-YP851818MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Sco2重組蛋白
貨號：

CSB-EP851818MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Sco2重組蛋白
貨號：

CSB-EP851818MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Sco2重組蛋白
貨號：

CSB-BP851818MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Sco2重組蛋白
貨號：

CSB-MP851818MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sco2
Uniprot No.：

Q8VCL2
別名：

Sco2; Protein SCO2 homolog; mitochondrial
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
表達(dá)區(qū)域：

-
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
基因功能參考文獻(xiàn)：
1. Sco2 deficient mice develop increased adiposity, liver steatosis, and insulin resistance. PMID: 28428045
2. Data suggest that physical exercise attenuates age-related changes in mitochondrial COX biogenesis and p53 activity targeting SCO2 and mitochondria, and thereby induces antisenescent and protective effects in cardiac muscle. PMID: 21750704
3. Results describe the tissue distribution of SCO1 and SCO2 in mouse and human tissues. PMID: 20864674
4. To understand the biological role of SCO2, mice harboring both a Sco2 knock-out (KO) allele and a Sco2 knock-in (KI) E129K allele, corresponding to the common E140K mutation in humans, were studied. PMID: 19837698
5. findings show that p53 modulates the balance between the utilization of respiratory and glycolytic pathways; identifed Synthesis of Cytochrome c Oxidase 2 (SCO2) as the downstream mediator of this effect PMID: 16728594
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亞細(xì)胞定位：

Mitochondrion inner membrane; Single-pass membrane protein.
蛋白家族：

SCO1/2 family
組織特異性：

Expressed in retina, retinal pigment epithelium, and sclera.
數(shù)據(jù)庫鏈接：

KEGG: mmu:100126824

STRING: 10090.ENSMUSP00000131943

UniGene: Mm.287977