Recombinant Mouse Protein APCDD1 (Apcdd1), partial

中文名稱：

Recombinant Mouse Protein APCDD1(Apcdd1),partial
貨號：

CSB-YP661021MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Protein APCDD1(Apcdd1),partial
貨號：

CSB-EP661021MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Protein APCDD1(Apcdd1),partial
貨號：

CSB-EP661021MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Protein APCDD1(Apcdd1),partial
貨號：

CSB-BP661021MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Protein APCDD1(Apcdd1),partial
貨號：

CSB-MP661021MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Apcdd1
Uniprot No.：

Q3U128
別名：

Apcdd1; Drapc1Protein APCDD1; Adenomatosis polyposis coli down-regulated 1 protein homolog
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins.
基因功能參考文獻：
1. these novel findings suggest that APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR-130 during diet-induced obesity may contribute to impaired adipogenic differentiation and obesity-related metabolic disease. PMID: 28242765
2. Suggest that APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating epithelial rearrangement. PMID: 26170146
3. mouse Drapc1 is a novel in vivo target gene of Wnt/beta-catenin signaling pathway PMID: 15465500
亞細(xì)胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

APCDD1 family
數(shù)據(jù)庫鏈接：

KEGG: mmu:494504

STRING: 10090.ENSMUSP00000094302

UniGene: Mm.391102