Recombinant Mouse Pro-neuregulin-3, membrane-bound isoform (Nrg3), partial

中文名稱：

小鼠Nrg3重組蛋白
貨號：

CSB-YP016079MO1
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nrg3重組蛋白
貨號：

CSB-EP016079MO1
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nrg3重組蛋白
貨號：

CSB-EP016079MO1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nrg3重組蛋白
貨號：

CSB-BP016079MO1
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nrg3重組蛋白
貨號：

CSB-MP016079MO1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nrg3
Uniprot No.：

O35181
別名：

Nrg3; Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors.
基因功能參考文獻：
1. Studied the physiologic role of neuregulin3 (NRG3) in regulating glutamatergic transmission in pyramidal neurons. Found NRG3 regulates the SNARE-complex assembly, and NRG3 knockout causes display behavior deficits related to mental illness. PMID: 29463705
2. Nrg3 is therefore a critical mediator in the assembly of cortical inhibitory circuits. PMID: 28147272
3. This study demonistrated that Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action. PMID: 24703509
4. NRG1beta and NRG3 can promote the proliferation of mouse spermatogonia. PMID: 21837948
5. a Neuregulin3 signaling pathway is involved in specification of mammary gland morphogenesis PMID: 16140987
6. used positional cloning to narrow the interval containing scaramanga (ska) to a 75.6-kb interval containing the distal part of the Neuregulin3 (Nrg3) gene PMID: 16140987
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亞細胞定位：

[Pro-neuregulin-3, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-3]: Secreted.
蛋白家族：

Neuregulin family
組織特異性：

Expressed in sympathetic, motor, and sensory neurons.
數據庫鏈接：

KEGG: mmu:18183

STRING: 10090.ENSMUSP00000136884

UniGene: Mm.258705