Recombinant Mouse PR domain zinc finger protein 13 (Prdm13)

中文名稱：

小鼠Prdm13重組蛋白
貨號：

CSB-YP018642MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Prdm13重組蛋白
貨號：

CSB-EP018642MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Prdm13重組蛋白
貨號：

CSB-EP018642MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Prdm13重組蛋白
貨號：

CSB-BP018642MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Prdm13重組蛋白
貨號：

CSB-MP018642MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Prdm13
Uniprot No.：

E9PZZ1
別名：

Prdm13; PR domain zinc finger protein 13; EC 2.1.1.-; PR domain-containing protein 13
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-754
氨基酸序列

MPAHVTPRTE DARRGAGPSS ACGCSWFCHL RPVEDPASPS VCLAAVATMH GTSRTSATSV NADCCIPAGL RLGPVPGTFK LGKYLSDRRE PGPKKKVRMV RGELVDESGG SPLEWIGLIR AARNPQEQTL EAIADLPGGQ IFYRALRDVQ PGEELTVWYS NSLAQWFDIP TTATPTHDEK GEERYICWYC WRTFRYPNSL KAHLRFHCVL SGGGGRAFLP QEHAARPGAS PVAEGLGLPP KPTVPDLTAP VQAIALRPQA PAAQLAQACG ARESIKREAS LAPLATSPPP GKWGTPKKGK EQPDRAHSQF LGIVGGSSGG GGGLPFYPGV RSAFKPAGLA RAAAQSDPYR EEGGGKGPGL ALGRLLGGGR AGGRPGSGES PAGHHHHHHH AHHHHHHHPK CLLAGEPPPA GLPCPGALRA FPLLAGHPEE ASAFKHVERA PPAAATTSLP SARYAALPAP GLPVERCALQ PLDGGSLKAY PGGGGGGECS PLPAVMPAFT VYSGDLLYGP PAAYYPLKLH LGGLLKYPES ISYLSGPAAA AAAAAAAAAA AAAIGPAELG SLASIDREIA MHTQQLSEMA AGKSRARLDS GTLPPAVVAA TGPGGGGGGG SAAGKPKTGH LCLYCGKLYS RKYGLKIHMR THTGYKPLKC KVCLRPFGDP SNLNKHIRLH AEGNTPYRCE FCGKVLVRRR DLERHVKSRH PGQSLMAKAG DGPGPEPSYA LEPGDPKSED SDVDVCFTDD QSDPEAGGRG EHDS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in transcriptional regulation.
基因功能參考文獻：
1. The findings highlight the function of PRDM13 in repressing the activity of basic helix-loop-helix transcriptional activators that together are required to achieve precise neuronal specification during mouse development. PMID: 28850031
2. data show that Prdm13 is not required for amacrine fate as a class, but is essential for the formation of Ebf3+ amacrine cell subtypes. Rather than driving subtype identity, Prdm13 may act by restricting competing fate programs to maintain identity and survival. PMID: 29258872
3. Findings indicate that Prdm13/Nkx2-1-mediated signaling in the DMC declines with advanced age, leading to decreased sleep quality and increased adiposity. PMID: 25546159
4. Targeted deletion of Prdm13 leads to a specific reduction of amacrine cells and changes visual sensitivity. PMID: 25995483
亞細胞定位：

Nucleus.
蛋白家族：

Class V-like SAM-binding methyltransferase superfamily
數據庫鏈接：

KEGG: mmu:230025

STRING: 10090.ENSMUSP00000092761

UniGene: Mm.208541