Recombinant Mouse Neuropeptide S (Nps)

中文名稱：

小鼠Nps重組蛋白
貨號：

CSB-YP016026MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nps重組蛋白
貨號：

CSB-EP016026MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nps重組蛋白
貨號：

CSB-EP016026MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nps重組蛋白
貨號：

CSB-BP016026MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nps重組蛋白
貨號：

CSB-MP016026MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nps
Uniprot No.：

P0C0P8
別名：

Nps; Neuropeptide S
種屬：

Mus musculus (Mouse)
蛋白長度：

Cytoplasmic domain
表達區域：

70-89
氨基酸序列

S FRNGVGSGAK KTSFRRAKQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations.
基因功能參考文獻：
1. Study showed that the actions of neuropeptide S influenced the excitability of dorsal raphe and laterodorsal tegmentum neurons, which could play a role in the anxiolytic and arousal-promoting effects of this peptide. PMID: 28655610
2. NPS-/- mice display significant deficits in exploratory activity, long-term memory and arousal. PMID: 28548278
3. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN. PMID: 26239581
4. These data provide evidence for a direct interaction between the corticotropin-releasing factor and the NPS system and thereby extend previous observations of NPS-modulated stress responsiveness towards a mechanistic level. PMID: 22570383
5. Neuropeptide S knock-out mice display deficits in inhibitory avoidance memory indicating involvement in central noradrenergic systems. PMID: 21150909
6. Results describe the neuroanatomical, molecular, and functional aspects of neuropeptide S-producing neurons in the mouse brain. PMID: 21452230
7. These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats. PMID: 21452235
8. results demonstrate that neuropeptide S and NPSR1 regulate respiratory function through a central nervous system-mediated pathway PMID: 21167892
9. Data suggest that lithium evokes antagonistic effects on the mediation of hyperlocomotion and protection against lipid peroxidation induced by neuropeptide S. PMID: 19616051
10. analysis of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus PMID: 18628994
11. NPS facilitates spatial memory and mitigates MK801-induced spatial memory impairment in mice. PMID: 19429110
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亞細胞定位：

Secreted.
數據庫鏈接：

KEGG: mmu:100043254

STRING: 10090.ENSMUSP00000095597

UniGene: Mm.192092