Recombinant Mouse Leucine-rich repeat and calponin homology domain-containing protein 1 (Lrch1)

中文名稱：

小鼠Lrch1重組蛋白
貨號：

CSB-YP013071MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Lrch1重組蛋白
貨號：

CSB-EP013071MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Lrch1重組蛋白
貨號：

CSB-EP013071MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Lrch1重組蛋白
貨號：

CSB-BP013071MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Lrch1重組蛋白
貨號：

CSB-MP013071MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Lrch1
Uniprot No.：

P62046
別名：

Lrch1; Chdc1; Kiaa1016; Leucine-rich repeat and calponin homology domain-containing protein 1; Calponin homology domain-containing protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-709
氨基酸序列

MATPGSEPQA FAPALSVTAL HPHLHQHHQH HQHHQHHGGT GGTGFNLPLN RGLERALEEA ANSGGLNLSA RKLKEFPRTT APGHDLSDTV RADLSKNRLV EVPMELCQFV SLEILNLYHN CIRVIPEAIV NLQMLTHLNL SRNQLSALPA CLCGLPLKVL IASNNKLGSL PEEIGQLKQL MELDVSCNEI TALPQQIGQL KSLRELNVRR NYLKVLPPEL VDLPLVKFDF SCNKVLVIPV CFREMKQLQV LLLENNPLQS PPAQICTKGK VHIFKYLSIQ ACQIKTSDSL YLPTIERPHL HQHVEDSKKD SDSGVGSDNG DKRLSATEPS DEDTVSLNAP MSNIVEEDQT IKEDACHRLT PTKGEFQPKP SILGDSGISG QEREQLAGRA DARHSGLMNY IKDQAEDCEE LLRIEEDAHW HMEELLNSSK DRELDIAMIE QLREAELLQD PNGLSADIIE RSILNLFPMD SGEASEFPDP SLNGQLQLET SPDREVQNDL MLQSNGSQYS PNEIRENSPS VSPTANITAP FGLKPRSGSW CPEEVQGSLQ AESSPRRPQL LSRHVFLRPQ RNLESIDPQF TIRRKMEQMR EEKELVEQLR ESIEMRLKVT LHEDLGAALM DGVVLCHLAN HVRPRSVASI HVPSPAVPKL SMAKCRRNVE NFLEACRKLG VPEEKLCLPH HILEEKGLVK VGTTVQALLD VTVTKALFT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration in response to chemokine stimulation.
基因功能參考文獻：
1. LRCH1 as a novel effector to restrain PKCalpha-DOCK8-Cdc42 module-induced T cell migration and ameliorate EAE. PMID: 28028151
亞細胞定位：

Cytoplasm.
數據庫鏈接：

KEGG: mmu:380916

STRING: 10090.ENSMUSP00000086363

UniGene: Mm.288868