Recombinant Mouse Kelch-like protein 6 (Klhl6)

中文名稱：

小鼠Klhl6重組蛋白
貨號：

CSB-YP740929MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Klhl6重組蛋白
貨號：

CSB-EP740929MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Klhl6重組蛋白
貨號：

CSB-EP740929MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Klhl6重組蛋白
貨號：

CSB-BP740929MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Klhl6重組蛋白
貨號：

CSB-MP740929MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Klhl6
Uniprot No.：

Q6V595
別名：

Klhl6Kelch-like protein 6
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-619
氨基酸序列

MAGQRGACTM SDVVERSLEG PLALTTDKSS QKRGDLVEIL TGEKVKFDDT RLSLILQNGL ETLREENALT DVILCVDVQE FSCHRVVLAA ASNYFRAMFC NDLKEKYEKR IIIKGVDAET MHTLLVYTYT SKALITKQNV QRVLEAANLF QFLQLVDACA SFLTEALNPE NCIGILRLAD THSLDSLKMQ VQSYIIQNFV QILNSEEFLE LPVDTLYHIL RSDDLCVTEE AQVFETVMSW VRHKQSERLC LLPCVLENVR LPLLDPWYFV EMVEADPLIR QCPEVFPLLQ EARMYHLSGN EIISERTKPR MHEFQSEVFM IIGGCTKDER FVAEVTCLDP LRRSRLEVAK LPLTEHELES ENKKWVEFAC VTLKNEVYIS GGKETQHDVW KYNSSINKWI QIEYLNIGRW RHKMVVLGGK VYVLGGFDGL QRINNVETYD PFHNCWSEAA PLHVHVSSFA ATSHKKKLYV IGGGPNGKLA TDKTQCYDPS TNKWVLKSAM PVEAKCINAV SFQDHIYVVG GAMRALYAYS PLEDSWCLVT QLSHERASCG IAPCNNKLYI TGGRDEKNEV IATVLCWDPE AQKLTEECVL PRGVSHHGSV TIRKSYTHIR RVVPGAVSV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in B-lymphocyte antigen receptor signaling and germinal center formation.
基因功能參考文獻：
1. report that KLHL6, which is recurrently mutated in B cell lymphomas, is an off-target of the normal somatic hypermutation process taking place in germinal center (GC) B cells leaving open whether, despite the lack of impact of Klhl6 deficiency on GC B cell expansion, mutants could contribute to the oncogenic process PMID: 28807996
組織特異性：

Expressed in embryonic blood vessel endothelial cells but not in the vasculature of adult organs. In adults, detected at high levels in hematopoietic and lymphoid organs.
數據庫鏈接：

KEGG: mmu:239743

STRING: 10090.ENSMUSP00000053023

UniGene: Mm.86699