Recombinant Mouse Inverted formin-2 (Inf2), partial

中文名稱：

小鼠Inf2重組蛋白
貨號：

CSB-YP606358MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Inf2重組蛋白
貨號：

CSB-EP606358MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Inf2重組蛋白
貨號：

CSB-EP606358MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Inf2重組蛋白
貨號：

CSB-BP606358MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Inf2重組蛋白
貨號：

CSB-MP606358MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Inf2
Uniprot No.：

Q0GNC1
別名：

Inf2; Inverted formin-2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Severs actin filaments and accelerates their polymerization and depolymerization.
基因功能參考文獻：
1. These data support a critical regulatory role for INF2 in trophoblast invasion-a necessary process for placentation. PMID: 29309034
2. In mice, normal INF2 function is not required for glomerular development but normal INF2 is required for regulation of the actin-based behaviors necessary for response to and/or recovery from injury. PMID: 27350175
3. Data highlight a unique mechanism of formin action in which mDia1 and INF2 function in series to stabilize MTs and point to IQGAP1 as a scaffold that facilitates the activation of one formin by another. PMID: 27030671
4. The perinuclear actin rim structure colocalized with INF2 on stimulation, and INF2 depletion resulted in attenuation of the rim formation. PMID: 25941386
5. Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture. PMID: 21998196
6. Data suggest a role for INF1 in microtubule modification and potentially in coordinating microtubule and F-actin structure. PMID: 18815276
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亞細胞定位：

Cytoplasm, perinuclear region.
蛋白家族：

Formin homology family
數據庫鏈接：

KEGG: mmu:70435

STRING: 10090.ENSMUSP00000098591

UniGene: Mm.250193