Recombinant Mouse GSK-3-binding protein FRAT2 (Frat2)

中文名稱：

小鼠Frat2重組蛋白
貨號：

CSB-YP815633MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Frat2重組蛋白
貨號：

CSB-EP815633MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Frat2重組蛋白
貨號：

CSB-EP815633MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Frat2重組蛋白
貨號：

CSB-BP815633MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Frat2重組蛋白
貨號：

CSB-MP815633MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Frat2
Uniprot No.：

Q8K025
別名：

Frat2GSK-3-binding protein FRAT2; Frequently rearranged in advanced T-cell lymphomas 2; FRAT-2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-231
氨基酸序列

MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD RLIVQIGETL QLDTAHDRPA SPCAAPGPPP APPRVLAALS ADKTGTPARR LLRPTGSAET GDPAPPGAVR CVLGERGRVR GRSAPYCVAE IAPGASALPG PGRRGWLPGS VASHRIQQRR WTAGGARAAD DDPHRLLQQL VLSGNLIKEA VRRLQRAVAA VAATSPASAP GSGGGRSGPD SVTLQPSGAW L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.
基因功能參考文獻：
1. Data show that MLL fusion oncogenes maintain leukemia-associated Rac GTPases activity by regulating Frat gene expression, specifically Frat2. PMID: 23074275
2. Data show that that Frat synergizes with Diversin in the activation of JNK/AP-1 signaling. PMID: 19802005
蛋白家族：

GSK-3-binding protein family
數據庫鏈接：

KEGG: mmu:212398

STRING: 10090.ENSMUSP00000052788

UniGene: Mm.222723