Recombinant Mouse Fibronectin type III domain-containing protein 3B (Fndc3b), partial

中文名稱：

小鼠Fndc3b重組蛋白
貨號：

CSB-YP764681MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Fndc3b重組蛋白
貨號：

CSB-EP764681MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Fndc3b重組蛋白
貨號：

CSB-EP764681MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Fndc3b重組蛋白
貨號：

CSB-BP764681MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Fndc3b重組蛋白
貨號：

CSB-MP764681MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Fndc3b
Uniprot No.：

Q6NWW9
別名：

Fndc3b; Fad104; Kiaa4164; Ns5abp37; Fibronectin type III domain-containing protein 3B; Factor for adipocyte differentiation 104; HCV NS5A-binding protein 37
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be positive regulator of adipogenesis.
基因功能參考文獻：
1. miR-215-5p is a negative regulator of adipocyte differentiation through post-transcriptional regulation of FNDC3B and CTNNBIP1 during early adipogenesis PMID: 27521659
2. fad104 suppressed anchorage-independent growth of melanoma cells, and the N-terminal region of FAD104 is essential for inhibiting malignant transformation and STAT3 activity PMID: 26948083
3. It contribute not only to adipogenesis but also to other physiological events like pre-implantation in embryonic developments. PMID: 27040346
4. down-regulation of Smad1/5/8 phosphorylation by FAD104 is dependent on the N-terminal region of FAD104 and that fad104 functions as a novel negative regulator of BMP/Smad signaling and is required for proper development for calvarial bone. PMID: 24052261
5. Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation PMID: 21704616
6. fad104 reciprocally regulates differentiation of adipocytes and osteoblast; functions as a positive regulator in adipocyte differentiation and as a negative regulator in osteoblast differentiation. PMID: 20493170
7. Fad104 is essential for the survival of newborns just after birth and important for cell proliferation, adhesion, spreading and migration. PMID: 19138685
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亞細胞定位：

Membrane; Single-pass membrane protein.
蛋白家族：

FNDC3 family
數據庫鏈接：

KEGG: mmu:72007

STRING: 10090.ENSMUSP00000041495

UniGene: Mm.38832