Recombinant Mouse Exportin-7 (Xpo7), partial

中文名稱：

小鼠Xpo7重組蛋白
貨號：

CSB-YP866806MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Xpo7重組蛋白
貨號：

CSB-EP866806MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Xpo7重組蛋白
貨號：

CSB-EP866806MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Xpo7重組蛋白
貨號：

CSB-BP866806MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Xpo7重組蛋白
貨號：

CSB-MP866806MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Xpo7
Uniprot No.：

Q9EPK7
別名：

Xpo7; Kiaa0745; Ranbp16; Exportin-7; Exp7; Ran-binding protein 16
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
基因功能參考文獻：
1. Knockdown of Xpo7 in primary fetal liver erythroblasts resulted in severe inhibition of chromatin condensation and enucleation but otherwise had little effect on erythroid differentiation, including hemoglobin accumulation. PMID: 25092175
2. This study demonstrateg that exportin-7 responds to ischemia in astrocytes. PMID: 25250856
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Exportin family
組織特異性：

Highly expressed in testis and spleen, moderate in kidney and liver and low in heart, brain, lung and skeletal muscle.
數據庫鏈接：

KEGG: mmu:65246

STRING: 10090.ENSMUSP00000022696

UniGene: Mm.152987