Recombinant Mouse Endothelin-converting enzyme-like 1 (Ecel1), partial

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Stock}

中文名稱：

小鼠Ecel1重組蛋白
貨號：

CSB-EP878117MO
說明書：

MSDS Datasheet
規(guī)格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產(chǎn)品詳情
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靶點詳情

產(chǎn)品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Ecel1
Uniprot No.：

Q9JMI0
別名：

Ecel1; Dine; XceEndothelin-converting enzyme-like 1; EC 3.4.24.-; Damage-induced neuronal endopeptidase; Xce protein
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
來源：

E.coli
分子量：

13.7 kDa
表達區(qū)域：

1-61aa
氨基酸序列

MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPRGSGRSASGSRSGLPRWNRREVC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged and C-terminal Myc-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
基因功能參考文獻：
1. This study demonstrated that the ECEL1/DINE G607S and C760R mutations both lead to motor innervation defects as primary causes in ECEL1-mutated congenital contracture disorders. PMID: 29132416
2. DINE is expressed in cranial and spinal motor neurons both embryonically and after CNS injury PMID: 27656015
3. DINE enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. PMID: 28569783
4. Using two different DINE mutant mice, study found that DINE functional disruption leads to impaired axonal arborization of motor nerves in limb muscles. PMID: 26951213
5. The data of this study suggested that DINE is a crucial molecule in distal axonal arborization into muscle to establish neuromuscular junctions. PMID: 20484637
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亞細胞定位：

Membrane; Single-pass type II membrane protein.
蛋白家族：

Peptidase M13 family
數(shù)據(jù)庫鏈接：

KEGG: mmu:13599

STRING: 10090.ENSMUSP00000027463

UniGene: Mm.140765