Recombinant Mouse Cortistatin (Cort)

中文名稱：

Recombinant Mouse Cortistatin(Cort)
貨號：

CSB-YP005821MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cortistatin(Cort)
貨號：

CSB-EP005821MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cortistatin(Cort)
貨號：

CSB-EP005821MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cortistatin(Cort)
貨號：

CSB-BP005821MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cortistatin(Cort)
貨號：

CSB-MP005821MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cort
Uniprot No.：

P56469
別名：

CortCortistatin [Cleaved into: Cortistatin-14]
種屬：

Mus musculus (Mouse)
蛋白長度：

Cytoplasmic domain
表達區域：

96-109
氨基酸序列

PCKNF FWKTFSSCK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice. PMID: 27901064
2. Endogenous SST and CORT distinctly impact on DMBA-induced mammary gland tumorigenesis , in a manner that is strongly dependent on the metabolic/endocrine milieu (lean vs. obese status). PMID: 26956474
3. This study demonistrated that Cortistatin attenuates inflammatory pain via spinal and peripheral actions. PMID: 24333694
4. endogenous CORT is essential for the obesity-induced changes in insulin expression/secretion observed in mice PMID: 23469081
5. Cortistatin emerges as a natural endogenous regulator of smooth muscle cells under pathological conditions and an attractive candidate for the pharmacological management of vascular diseases that course with neointimal lesion formation. PMID: 23595952
6. the role of endogenous CST is different from SST; CST exerted an unexpected stimulatory role on prolactin secretion PMID: 21971153
7. Cortistatin mRNA concentration in the hippocampus and dentate gyrus is significantly increased in aged non-transgenic (Tg) mice compared with young non-Tg mice. PMID: 15364032
顯示更多

收起更多
亞細胞定位：

Secreted.
蛋白家族：

Somatostatin family
組織特異性：

Expressed in a subset of GABAergic cells in the cortex and hippocampus.
數據庫鏈接：

KEGG: mmu:12854

STRING: 10090.ENSMUSP00000030815

UniGene: Mm.6204