Recombinant Mouse Complement component C8 gamma chain (C8g)

中文名稱：

Recombinant Mouse Complement component C8 gamma chain(C8g)
貨號：

CSB-YP823734MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Complement component C8 gamma chain(C8g)
貨號：

CSB-EP823734MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Complement component C8 gamma chain(C8g)
貨號：

CSB-BP823734MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Complement component C8 gamma chain(C8g)
貨號：

CSB-MP823734MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

C8g
Uniprot No.：

Q8VCG4
別名：

C8gComplement component C8 gamma chain
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

21-202
氨基酸序列

QRTRKPIGST SPISTIQAQV NFSAQKFAGT WLLVAVGSSC RFLQEQGHRA EATTLHAAPQ GAAMAVSTFR KLDGICWQVR QLFENTGVPG RFLFQVSRAR GPVHMVVAET DYQSFAILYL EQGRKLSVKL YVRSLPVNDS VLDVFERRVR EANLTEDQIL FFPKYGFCET ADQLHILNEV PR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.
基因功能參考文獻：
1. A review of the human C8 gamma ortholog. PMID: 11058761
2. This is a study of the human C8 orthologs. Binding of C8 gamma subunit to C8 beta is dependent on the thrombospondin type 1 module, low-density lipoprotein receptor class A module, and membrane attack complex/perforin domain of C8 beta. PMID: 12220191
3. This is a study of the human orthologs of C8 alpha, beta, and gamma. C8 gamma is not required for complement-mediated killing of Gram-negative bacteria. PMID: 12413696
4. Results describe the crystal structure of the human ortholog C8 alpha MACPF domain disulfide-linked to C8 gamma (alphaMACPF-gamma) at 2.15 A resolution. PMID: 18440555
亞細胞定位：

Secreted.
蛋白家族：

Calycin superfamily, Lipocalin family
數據庫鏈接：

KEGG: mmu:69379

STRING: 10090.ENSMUSP00000041855

UniGene: Mm.24596