Recombinant Mouse Coiled-coil domain-containing protein 80 (Ccdc80), partial

中文名稱：

Recombinant Mouse Coiled-coil domain-containing protein 80(Ccdc80) ,partial
貨號：

CSB-YP851256MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Coiled-coil domain-containing protein 80(Ccdc80) ,partial
貨號：

CSB-EP851256MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Coiled-coil domain-containing protein 80(Ccdc80) ,partial
貨號：

CSB-EP851256MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Coiled-coil domain-containing protein 80(Ccdc80) ,partial
貨號：

CSB-BP851256MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Coiled-coil domain-containing protein 80(Ccdc80) ,partial
貨號：

CSB-MP851256MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ccdc80
Uniprot No.：

Q8R2G6
別名：

Ccdc80; UrbCoiled-coil domain-containing protein 80; Up-regulated in BRS-3 deficient mouse
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Promotes cell adhesion and matrix assembly.
基因功能參考文獻：
1. DRO1 is a crucial regulator of energy homeostasis in vivo and functions as an inhibitor of adipogenesis in primary cells. PMID: 27645901
2. This report characterizes a new mouse model for the study of colorectal cancer and establishes DRO1 (CCDC80) as a tumor suppressor via a mechanism involving ERK phosphorylation. PMID: 25053805
3. Ccdc80 is a novel betacat-regulated gene in adrenocortical cells PMID: 25029241
4. Data indicate that embryonic fibroblasts from cl2/coiled-coil domain-containing protein 80 (ccdc80) knock-out mice showed higher proliferation rate and lower susceptibility to apoptosis. PMID: 25497869
5. Results suggest that Ccdc80 is a novel modulator of glucose and energy homeostasis during diet-induced obesity. PMID: 22753645
6. Downregulated during osteoblastic differentiation of bone marrow stromal cells. Suggests role in skeletogenesis. PMID: 15325258
7. In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes. PMID: 18178152
8. Ccdc80 plays dual roles in adipogenesis by mechanisms that involve at least in part down-regulation of Wnt/beta-catenin signaling and induction of C/EBPalpha and peroxisome proliferator-activated receptor gamma. PMID: 19141617
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

CCDC80 family
組織特異性：

Expressed in brain, stomach, colon, rectum, liver, lung, kidney, adipocytes and testis.
數據庫鏈接：

KEGG: mmu:67896

STRING: 10090.ENSMUSP00000058752

UniGene: Mm.181074