Recombinant Mouse CD177 antigen (Cd177), partial

中文名稱：

Recombinant Mouse CD177 antigen(Cd177) ,partial
貨號(hào)：

CSB-YP854505MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Mouse CD177 antigen(Cd177) ,partial
貨號(hào)：

CSB-EP854505MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Mouse CD177 antigen(Cd177) ,partial
貨號(hào)：

CSB-EP854505MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse CD177 antigen(Cd177) ,partial
貨號(hào)：

CSB-BP854505MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse CD177 antigen(Cd177) ,partial
貨號(hào)：

CSB-MP854505MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cd177
Uniprot No.：

Q8R2S8
別名：

Cd177CD177 antigen; CD antigen CD177
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Partial
表達(dá)區(qū)域：

-
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production. In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration. Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro. However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo. Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils. By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis.
基因功能參考文獻(xiàn)：
1. Herein we established a novel genetic mouse model to study the role of CD177 and found that CD177 plays an important role in neutrophils. PMID: 25359465
亞細(xì)胞定位：

Cell membrane; Single-pass type IV membrane protein.
組織特異性：

Expressed in neutrophils.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:68891

STRING: 10090.ENSMUSP00000064934

UniGene: Mm.292848