Recombinant Mouse Alpha-defensin 5 (Defa5)

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中文名稱：

Recombinant Mouse Alpha-defensin 5(Defa5)
品名簡稱：

Recombinant Mouse Defa5 protein
貨號：

CSB-EP006657MO
說明書：

MSDS Datasheet
規(guī)格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產(chǎn)品詳情
產(chǎn)品評價
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靶點詳情

產(chǎn)品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

Defa5
Uniprot No.：

P28312
別名：

Defa5; Defcr5; Alpha-defensin 5; Defensin-related cryptdin-5
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

31.2kDa
表達(dá)區(qū)域：

59-93aa
氨基酸序列

SKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal GST-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產(chǎn)品描述：

Recombinant Mouse Defa5 is an E.coli?cell-expressed protein (Full Length of Mature Protein). E.coli?expression systems are popular because bacteria are easy to culture, grow fast and produce high yields of recombinant protein. Traditional strategies for Mouse Defa5 recombinant protein expression involve transforming the recombinant plasmid into the E. coli host. The cells were directly replicated, transcribed and translated, and IPTG was added to express the desired protein. Typically, the cells are then lysed to extract the expressed protein for subsequent purification. Also, many proteins become insoluble as inclusion bodies that are very difficult to recover, so mild conditions and subsequent cumbersome protein-refolding procedures are used to ensure the final provided protein is soluble.
Defa5 is a gene encoding a protein named alpha-defensin 5 which belongs to alpha-defensin family (also reffered to a family of microbicidal and cytotoxic peptides). The members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif, which are involved in host defense, and help to maintain homeostasis of intestinal microbiota. Emerging evidence has reported that human alpha defensin 5 is highly expressed in secretory granules of crypt Paneth cells (PCs) of the small intestine (ileum) and is a candidate biomarker to delineate inflammatory bowel disease.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
亞細(xì)胞定位：

Secreted.
蛋白家族：

Alpha-defensin family
數(shù)據(jù)庫鏈接：

STRING: 10090.ENSMUSP00000093074

UniGene: Mm.426634