Recombinant Mouse Abhydrolase domain-containing protein 4 (Abhd4)

中文名稱：

Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4)
貨號：

CSB-YP823742MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4)
貨號：

CSB-EP823742MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4)
貨號：

CSB-EP823742MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4)
貨號：

CSB-BP823742MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4)
貨號：

CSB-MP823742MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Abhd4
Uniprot No.：

Q8VD66
別名：

Abhd4(Lyso)-N-acylphosphatidylethanolamine lipase; EC 3.1.1.-; Alpha/beta hydrolase domain-containing protein 4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-342
氨基酸序列

MADDLEQQPQ GWLSSWLPTW RPTSMSQLKN VEARILQCLQ NKFLARYVSL PNQNKIWTVT VSPEQKDRTP LVMVHGFGGG VGLWILNMDS LSARRTLHTF DLLGFGRSSR PTFPRDPEGA EDEFVASIET WRETMGIPTM ILLGHSLGGF LATSYSIKYP ERVKHLILVD PWGFPLRPTD PSEIRAPPTW VKAVASVLGR SNPLAVLRVA GPWGPGLVQR FRPDFKRKFA DFFEDDTISE YIYHCNAQNP SGETAFKAMM ESFGWARRPM LERIHLIRKD VPITMIYGAN TWIDTSTGKK VKMQRPDSYV RDMEIEGASH HVYADQPHIF NAVVEEICNS VD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
基因功能參考文獻：
1. These findings, taken together, designate ABHD4 as a principal regulator of N-acyl phospholipid metabolism in the mammalian nervous system. PMID: 25853435
2. Lysophospholipase/phospholipase B (EC 3.1.1.5) specific for N-acyl phosphatidylethanolamine (NAPE) suggesting a role in the biosynthesis of N-acyl ethanolamines including the endocannabinoid anandamide. PMID: 16818490
蛋白家族：

Peptidase S33 family, ABHD4/ABHD5 subfamily
組織特異性：

Highest levels in the CNS and in testis, intermediate levels in liver and kidney. Hardly detectable in heart.
數據庫鏈接：

KEGG: mmu:105501

STRING: 10090.ENSMUSP00000044134

UniGene: Mm.28771