Recombinant Mouse AP-3 complex subunit delta-1 (Ap3d1), partial

中文名稱：

Recombinant Mouse AP-3 complex subunit delta-1(Ap3d1) ,partial
貨號：

CSB-YP001876MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse AP-3 complex subunit delta-1(Ap3d1) ,partial
貨號：

CSB-EP001876MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse AP-3 complex subunit delta-1(Ap3d1) ,partial
貨號：

CSB-EP001876MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse AP-3 complex subunit delta-1(Ap3d1) ,partial
貨號：

CSB-BP001876MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse AP-3 complex subunit delta-1(Ap3d1) ,partial
貨號：

CSB-MP001876MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ap3d1
Uniprot No.：

O54774
別名：

Ap3d1; Ap3dAP-3 complex subunit delta-1; AP-3 complex subunit delta; Adaptor-related protein complex 3 subunit delta-1; Delta-adaptin; mBLVR1
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
基因功能參考文獻：
1. The linker of the delta-adaptin subunit of AP3 binds the VAMP7 longin domain and determines the structure of their complex. PMID: 22521722
2. This study demonstrated that distinct brain regions differentially regulate AP-3-dependent synaptic vesicle biogenesis. PMID: 20089890
3. Assembly and function of AP-3 complexes in cells expressing mutant subunits PMID: 11807095
4. Data suggest that adaptor-related protein complex 3 delta could be involved in the regulation of progenitor cell competence and the eventual ratio of resulting differentiated cells. PMID: 19631730
5. A null mutation in Ap3d in the mouse results in the mouse mutant "mocha" (mh). In addition to coat and eye color dilution and platelet storage pool deficiency, mocha mice have neurological impairment and are hyperactive. PMID: 9697856
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亞細胞定位：

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

Adaptor complexes large subunit family
數據庫鏈接：

KEGG: mmu:11776

STRING: 10090.ENSMUSP00000020420

UniGene: Mm.209294