Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor (vif)

中文名稱：

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor(vif)
貨號：

CSB-YP324686HLU
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor(vif)
貨號：

CSB-EP324686HLU
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor(vif)
貨號：

CSB-EP324686HLU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor(vif)
貨號：

CSB-BP324686HLU
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor(vif)
貨號：

CSB-MP324686HLU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

vif
Uniprot No.：

P18097
別名：

vifVirion infectivity factor; Vif; Q protein; SOR protein
種屬：

Human immunodeficiency virus type 2 subtype A (isolate BEN) (HIV-2)
蛋白長度：

full length protein
表達區域：

1-215
氨基酸序列

MEEDRNWIVV PTWRVPGRME KWHALVKYLK YRTKDLEEVR YVPHHKVGWA WWTCSRVIFP LQGKSHLEIQ AYWNLTPEKG WLSSHAVRLT WYTEKFWTDV TPDCADILIH STYFSCFTAG EVRRAIRGEK LLSCCNYPQA HKAQVPSLQY LALVVVQQND RPQRKGTARK QWRRDHWRGL RVAREDHRSL KQGGSEPSAP RAHFPGVAKV LEILA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Counteracts the innate antiviral activity of APOBEC3G. Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions. Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery. Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1. Binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology.
基因功能參考文獻：
1. Authors found that APOBEA3G, APOBEA3F, and APOBEA3H-hapII, but not APOBEA3D, were susceptible to HIV-2 Vif-induced degradation. PMID: 24942576
2. Functional analysis of Vif protein shows less restriction of human immunodeficiency virus type 2 by APOBEC3G. PMID: 15613310
亞細胞定位：

Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion.
蛋白家族：

Primate lentivirus group Vif protein family
數據庫鏈接：

KEGG: vg:1724712