Recombinant Human Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1)

中文名稱：

人RTN4IP1重組蛋白
貨號：

CSB-YP848832HU
規格：
來源：

Yeast
其他：

中文名稱：

人RTN4IP1重組蛋白
貨號：

CSB-EP848832HU
規格：
來源：

E.coli
其他：

中文名稱：

人RTN4IP1重組蛋白
貨號：

CSB-EP848832HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RTN4IP1重組蛋白
貨號：

CSB-BP848832HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人RTN4IP1重組蛋白
貨號：

CSB-MP848832HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RTN4IP1
Uniprot No.：

Q8WWV3
別名：

MGC12934; mitochondrial; NIMP; NOGO interacting mitochondrial protein; NOGO-interacting mitochondrial protein; Reticulon 4 interacting protein 1; Reticulon 4 interacting protein 1, mitochondrial; Reticulon-4-interacting protein 1; RT4I1_HUMAN; Rtn4ip1
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

41-396
氨基酸序列

TVMPAWVIDK YGKNEVLRFT QNMMMPIIHY PNEVIVKVHA ASVNPIDVNM RSGYGATALN MKRDPLHVKI KGEEFPLTLG RDVSGVVMEC GLDVKYFKPG DEVWAAVPPW KQGTLSEFVV VSGNEVSHKP KSLTHTQAAS LPYVALTAWS AINKVGGLND KNCTGKRVLI LGASGGVGTF AIQVMKAWDA HVTAVCSQDA SELVRKLGAD DVIDYKSGSV EEQLKSLKPF DFILDNVGGS TETWAPDFLK KWSGATYVTL VTPFLLNMDR LGIADGMLQT GVTVGSKALK HFWKGVHYRW AFFMASGPCL DDIAELVDAG KIRPVIEQTF PFSKVPEAFL KVERGHARGK TVINVV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.
基因功能參考文獻：
1. Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. PMID: 26593267
2. RTN4IP1 has a tumor-suppressive function and may regulate thyroid cancer progression. PMID: 23393170
相關疾病：

Optic atrophy 10 with or without ataxia, mental retardation, and seizures (OPA10)
亞細胞定位：

Mitochondrion outer membrane.
蛋白家族：

Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
組織特異性：

Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
數據庫鏈接：

HGNC: 18647

OMIM: 610502

KEGG: hsa:84816

STRING: 9606.ENSP00000358059

UniGene: Hs.155839