Recombinant Human Protein RFT1 homolog (RFT1), partial

中文名稱：

人RFT1重組蛋白
貨號：

CSB-YP846583HU
規格：
來源：

Yeast
其他：

中文名稱：

人RFT1重組蛋白
貨號：

CSB-EP846583HU
規格：
來源：

E.coli
其他：

中文名稱：

人RFT1重組蛋白
貨號：

CSB-EP846583HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RFT1重組蛋白
貨號：

CSB-BP846583HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人RFT1重組蛋白
貨號：

CSB-MP846583HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RFT1
Uniprot No.：

Q96AA3
別名：

RFT1; Protein RFT1 homolog
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
基因功能參考文獻：
1. showed that this patient was compound heterozygous for two mutations in the RFT1 gene: c.1325G>A (p.R442Q) and c.110G>T (p.R37L) PMID: 26892341
2. Six patients with RFT1-CDG show sensorineural deafness as part of a severe neurological syndrome PMID: 19856127
3. Identification of novel missense mutations in exon 12 of the RFT1 gene in adult siblings with congenital disorder of glycosylation (CDG) syndrome caused by RFT1 deficiency. PMID: 23111317
4. RFT1 deficiency in both yeast and human cells leads to the accumulation of incomplete DolPP-GlcNAc(2)Man(5) and to a profound glycosylation disorder in humans. PMID: 18313027
相關疾病：

Congenital disorder of glycosylation 1N (CDG1N)
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

RFT1 family
數據庫鏈接：

HGNC: 30220

OMIM: 611908

KEGG: hsa:91869

STRING: 9606.ENSP00000296292

UniGene: Hs.631910