Recombinant Human Protein FAM162A (FAM162A), partial

中文名稱：

人FAM162A重組蛋白
貨號(hào)：

CSB-YP836176HU1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人FAM162A重組蛋白
貨號(hào)：

CSB-EP836176HU1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人FAM162A重組蛋白
貨號(hào)：

CSB-EP836176HU1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FAM162A重組蛋白
貨號(hào)：

CSB-BP836176HU1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人FAM162A重組蛋白
貨號(hào)：

CSB-MP836176HU1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

FAM162A
Uniprot No.：

Q96A26
別名：

FAM162A; C3orf28; E2IG5; DC16; FWP001; Protein FAM162A; E2-induced gene 5 protein; Growth and transformation-dependent protein; HGTD-P
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly.
基因功能參考文獻(xiàn)：
1. Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer PMID: 20840676
2. Data indicate that HGTD-P is a new hypoxia-inducible factor 1 alpha-responsive proapoptotic molecule that activates mitochondrial apoptotic cascades. PMID: 15082785
3. Heat shock protein 90 physically interacts with HGTD-P. PMID: 16698020
4. human growth and transformation-dependent protein expression is a common occurrence during the progression from a normal gastric mucosa to an intestinal-type carcinoma and may be associated with tumor cell proliferation activity PMID: 19269009
5. HGTD-P plays a proapoptotic role in the developing rat brain following hypoxia-ischemia by activating caspase 3 and inducing the translocation of apoptosis-inducing factor (AIF) to the nucleus. PMID: 19520982
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亞細(xì)胞定位：

Mitochondrion membrane; Single-pass membrane protein.
蛋白家族：

UPF0389 family
數(shù)據(jù)庫鏈接：

HGNC: 17865

OMIM: 608017

KEGG: hsa:26355

STRING: 9606.ENSP00000419088

UniGene: Hs.584881