Recombinant Human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (DHTKD1), partial

中文名稱：

人DHTKD1重組蛋白
貨號：

CSB-YP842685HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人DHTKD1重組蛋白
貨號：

CSB-EP842685HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人DHTKD1重組蛋白
貨號：

CSB-EP842685HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人DHTKD1重組蛋白
貨號：

CSB-BP842685HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人DHTKD1重組蛋白
貨號：

CSB-MP842685HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

DHTKD1
Uniprot No.：

Q96HY7
別名：

AMOXAD; CMT2Q; Dehydrogenase E1 and transketolase domain containing 1; Dehydrogenase E1 and transketolase domain containing protein 1; Dehydrogenase E1 and transketolase domain-containing protein 1; DHTK1_HUMAN; dhtkd1; DKFZp762M115; KIAA1630; MGC3090; Probable 2 oxoglutarate dehydrogenase E1 component DHKTD1 mitochondrial; Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1; mitochondrial
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
表達區(qū)域：

-
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
基因功能參考文獻：
1. DHTKD1 encodes the E1 subunit of the alpha-ketoadipic acid dehydrogenase complex PMID: 25860818
2. DHTKD1 contributes to mitochondrial biogenesis and function maintenance. PMID: 24076469
3. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. PMID: 23141293
4. A nonsense mutation in DHTKD1 causes Charcot-Marie-Tooth disease type 2 in a large Chinese pedigree. PMID: 23141294
相關疾病：

Charcot-Marie-Tooth disease 2Q (CMT2Q); 2-aminoadipic 2-oxoadipic aciduria (AMOXAD)
亞細胞定位：

Mitochondrion.
蛋白家族：

Alpha-ketoglutarate dehydrogenase family
數(shù)據(jù)庫鏈接：

HGNC: 23537

OMIM: 204750

KEGG: hsa:55526

STRING: 9606.ENSP00000263035

UniGene: Hs.104980