Recombinant Human Long-chain fatty acid transport protein 1 (SLC27A1), partial

中文名稱：

人SLC27A1重組蛋白
貨號：

CSB-YP740768HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人SLC27A1重組蛋白
貨號：

CSB-EP740768HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人SLC27A1重組蛋白
貨號：

CSB-EP740768HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SLC27A1重組蛋白
貨號：

CSB-BP740768HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人SLC27A1重組蛋白
貨號：

CSB-MP740768HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SLC27A1
Uniprot No.：

Q6PCB7
別名：

SLC27A1; ACSVL5; FATP1Long-chain fatty acid transport protein 1; FATP-1; Fatty acid transport protein 1; EC 6.2.1.-; Solute carrier family 27 member 1
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier.
基因功能參考文獻：
1. Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression PMID: 26867681
2. Several proteins that are expressed in the epidermis have been proposed to facilitate the uptake of long-chain fatty acids (LCFA) in mammalian cells, CD36, fatty acid binding protein, and FATP. [review] PMID: 24120574
3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20965718
4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
5. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
6. FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase PMID: 20356843
7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
8. exogenously supplied fatty acids are preferentially channeled by an FATP1-linked mechanism into the TG biosynthetic pathway; such internalized lipids downregulate de novo sphingomyelin and cholesterol metabolism in growing 293 cells PMID: 12235169
9. FATP1 might play a role in post-prandial lipid metabolism and development of cardiovascular disease. PMID: 12818409
10. FATP1 stimulated transport and consumption of palmitate and oleate, which they channeled away from complete oxidation and toward TAG synthesis. PMID: 15897321
11. These data reveals the localization and points to a regulatory function of FATP1 in myotube mitochondria. PMID: 19361580
12. Observational study of gene-disease association. (HuGE Navigator) PMID: 18660489
13. Observational study of gene-disease association. (HuGE Navigator) PMID: 12818409
14. Observational study of gene-disease association. (HuGE Navigator) PMID: 15978856
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亞細胞定位：

Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm.
蛋白家族：

ATP-dependent AMP-binding enzyme family
組織特異性：

Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter.
數據庫鏈接：

HGNC: 10995

OMIM: 600691

KEGG: hsa:376497

STRING: 9606.ENSP00000252595

UniGene: Hs.363138