Recombinant Human Dihydropyrimidinase-related protein 4 (DPYSL4)

中文名稱：

人DPYSL4重組蛋白
貨號：

CSB-YP007172HU
規格：
來源：

Yeast
其他：

中文名稱：

人DPYSL4重組蛋白
貨號：

CSB-EP007172HU
規格：
來源：

E.coli
其他：

中文名稱：

人DPYSL4重組蛋白
貨號：

CSB-EP007172HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人DPYSL4重組蛋白
貨號：

CSB-BP007172HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人DPYSL4重組蛋白
貨號：

CSB-MP007172HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

DPYSL4
Uniprot No.：

O14531
別名：

Collapsin response mediator protein 3; CRMP 3; CRMP-3; CRMP3; Dihydropyrimidinase like 4; Dihydropyrimidinase related protein 4; Dihydropyrimidinase-related protein 4; DPYL4_HUMAN; DPYSL4; DRP 4; DRP-4; DRP4; ULIP 4; ULIP-4; ULIP4; UNC33 like phosphoprotein 4; UNC33-like phosphoprotein 4
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-572
氨基酸序列

MSFQGKKSIP RITSDRLLIR GGRIVNDDQS FYADVHVEDG LIKQIGENLI VPGGIKTIDA HGLMVLPGGV DVHTRLQMPV LGMTPADDFC QGTKAALAGG TTMILDHVFP DTGVSLLAAY EQWRERADSA ACCDYSLHVD ITRWHESIKE ELEALVKEKG VNSFLVFMAY KDRCQCSDSQ MYEIFSIIRD LGALAQVHAE NGDIVEEEQK RLLELGITGP EGHVLSHPEE VEAEAVYRAV TIAKQANCPL YVTKVMSKGA ADAIAQAKRR GVVVFGEPIT ASLGTDGSHY WSKNWAKAAA FVTSPPVNPD PTTADHLTCL LSSGDLQVTG SAHCTFTTAQ KAVGKDNFAL IPEGTNGIEE RMSMVWEKCV ASGKMDENEF VAVTSTNAAK IFNFYPRKGR VAVGSDADLV IWNPKATKII SAKTHNLNVE YNIFEGVECR GAPAVVISQG RVALEDGKMF VTPGAGRFVP RKTFPDFVYK RIKARNRLAE IHGVPRGLYD GPVHEVMVPA KPGSGAPARA SCPGKISVPP VRNLHQSGFS LSGSQADDHI ARRTAQKIMA PPGGRSNITS LS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
基因功能參考文獻：
1. DPYSL4 plays a key role in the tumor-suppressor function of p53 by regulating oxidative phosphorylation and the cellular energy supply via its association with mitochondrial supercomplexes, possibly linking to the pathophysiology of both cancer and obesity. PMID: 30061407
2. DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage PMID: 20499313
3. Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. PMID: 11771764
亞細胞定位：

Cytoplasm.
蛋白家族：

Metallo-dependent hydrolases superfamily, Hydantoinase/dihydropyrimidinase family
數據庫鏈接：

HGNC: 3016

OMIM: 608407

KEGG: hsa:10570

STRING: 9606.ENSP00000339850

UniGene: Hs.100058