Recombinant Human Diacylglycerol kinase kappa (DGKK), partial

中文名稱：

人DGKK重組蛋白
貨號：

CSB-YP702513HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人DGKK重組蛋白
貨號：

CSB-EP702513HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人DGKK重組蛋白
貨號：

CSB-EP702513HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人DGKK重組蛋白
貨號：

CSB-BP702513HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人DGKK重組蛋白
貨號：

CSB-MP702513HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

DGKK
Uniprot No.：

Q5KSL6
別名：

DGKKDiacylglycerol kinase kappa; DAG kinase kappa; EC 2.7.1.107; 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable).
基因功能參考文獻：
1. FMRP is mostly associated diacylglycerol kinase kappa (Dgkkappa), a master regulator that controls the switch between diacylglycerol and phosphatidic acid signaling pathways. PMID: 27233938
2. Dgkk appears to be a marker or mediator of squamous cell differentiation in development of mouse external genitalia. No association exists between Dgkk expression and formation of preputial cleft in the genital tubercle of diethylsilbestrol treated mice. PMID: 26162297
3. Studied the relationship between DGKK single nucleotide polymorphisms (SNPs) and hypospadias risk in the Han Chinese population. PMID: 25327554
4. Common variants in DGKK are strongly associated with risk of hypospadias PMID: 21113153
5. DGK kappa is a novel human type II diacylglycerol kinase PMID: 16210324
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亞細胞定位：

Cell membrane; Peripheral membrane protein.
蛋白家族：

Eukaryotic diacylglycerol kinase family
組織特異性：

Expressed in testis, and to a lesser extent in placenta.
數據庫鏈接：

HGNC: 32395

OMIM: 300837

KEGG: hsa:139189

UniGene: Hs.38132