Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial (ABCB8), partial

中文名稱：

Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial(ABCB8),partial
貨號：

CSB-YP868325HU
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial(ABCB8),partial
貨號：

CSB-EP868325HU
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial(ABCB8),partial
貨號：

CSB-EP868325HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial(ABCB8),partial
貨號：

CSB-BP868325HU
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human ATP-binding cassette sub-family B member 8, mitochondrial(ABCB8),partial
貨號：

CSB-MP868325HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ABCB8
Uniprot No.：

Q9NUT2
別名：

ABCB8; MABC1; MITOSUR; Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes.
基因功能參考文獻：
1. ABCB8 confers resistance through the protection of mitochondrial DNA from doxorubicin-induced DNA damage in a melanoma cell line. PMID: 19147539
2. mutations in ABCB8 and ABCB10 is not associated with acute myeloid leukemia. PMID: 19151771
亞細胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 49

OMIM: 605464

KEGG: hsa:11194

STRING: 9606.ENSP00000351717

UniGene: Hs.647118