Recombinant Goat Forkhead box protein L2 (FOXL2)

中文名稱：

Recombinant Goat Forkhead box protein L2(FOXL2)
貨號：

CSB-YP822644GO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Goat Forkhead box protein L2(FOXL2)
貨號：

CSB-EP822644GO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Goat Forkhead box protein L2(FOXL2)
貨號：

CSB-EP822644GO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Goat Forkhead box protein L2(FOXL2)
貨號：

CSB-BP822644GO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Goat Forkhead box protein L2(FOXL2)
貨號：

CSB-MP822644GO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FOXL2
Uniprot No.：

Q8MIP2
別名：

FOXL2Forkhead box protein L2
種屬：

Capra hircus (Goat)
蛋白長度：

full length protein
表達區域：

1-377
氨基酸序列

MMASYPEPED ASGALLAPET GRAAKEPEAP APPSPGKGGG GGAGAAPEKP DPAQKPPYSY VALIAMAIRE SAEKRLTLSG IYQYIIAKFP FYEKNKKGWQ NSIRHNLSLN ECFIKVPREG GGERKGNYWT LDPACEDMFE KGNYRRRRRM KRPFRPPPAH FQPGKGLFGA GGAAGGCGVA GAGADGYGYL APPKYLQSGF LNNSWPLPQP PSPMPYASCQ MAAAAAAAAA AAAAAGPGSP GAAAVVKGLA GPAASYGPYS RVQSMALPPG VVNSYNGLGG PPAAPPPPPH PHSHPHAHHL HAAAAPPPAP PHHGAAAPPP GQLSPASPAT AAPPAPAPTN APGLQFACAR QPELAMMHCS YWDHDSKTGA LHSRLDL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. Is a transcriptional repressor of STAR. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element. Is a regulator of CYP19 expression.
基因功能參考文獻：
1. results therefore identify FOXL2 as a bona fide female sex-determining gene in the goat PMID: 24485832
亞細胞定位：

Nucleus.
組織特異性：

Detected in the majority of somatic cells in the developing ovary.
數據庫鏈接：

KEGG: chx:102191377