Recombinant Fibulin-1 (fbl-1), partial

中文名稱：

秀麗隱桿線蟲fbl-1重組蛋白
貨號：

CSB-YP008452CXY
規(guī)格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲fbl-1重組蛋白
貨號：

CSB-EP008452CXY
規(guī)格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲fbl-1重組蛋白
貨號：

CSB-EP008452CXY-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲fbl-1重組蛋白
貨號：

CSB-BP008452CXY
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲fbl-1重組蛋白
貨號：

CSB-MP008452CXY
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

fbl-1
Uniprot No.：

O77469
別名：

fbl-1; fbln1; F56H11.1Fibulin-1
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Incorporated into fibronectin-containing matrix fibers. Plays a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Important for certain developmental processes and contributes to the supramolecular organization of ECM architecture, in particular to those of basement membranes.; Involved in regulating the shape and adhesion of cells in the developing pharynx, intestine, body-wall muscle and gonadal tissue. During gonadogenesis, regulates the width of gonads and the migration of distal tip cells (DTC). Together with type IV collagen let-2 and downstream of metalloprotease mig-17, recruits nidogen nid-1 to the gonad basement membrane thereby inducing basement membrane remodeling required for the directional migration of DTCs. Acts antagonistically with metalloprotease gon-1 to maintain optimal levels of type IV collagen emb-9 in the gonad basement membrane during gonadogenesis. Required for larval development.; Involved in the assembly of the flexible hemicentin-containing tracks found joining the pharynx and body-wall-muscle basement membranes.
基因功能參考文獻：
1. A series of deletion constructs shows that EGF repeats 4 and 5 are required for the hemicentin-dependent assembly and function of fibulin-1D in native locations. PMID: 22981695
2. There is a distinct developmental roles and hemicentin-dependent assembly for fibulin-1 splice variants PMID: 16120639
亞細胞定位：

[Isoform a]: Secreted, extracellular space, extracellular matrix, basement membrane.
蛋白家族：

Fibulin family
組織特異性：

Expressed in head muscle cells, anterior and posterior intestinal cells. Isoform a: Expressed in male and hermaphrodite gonad, anterior and posterior intestine and pharyngeal basement membranes, body-wall muscle, GLR cells, uterine attachment and mechanos
數(shù)據(jù)庫鏈接：

KEGG: cel:CELE_F56H11.1

STRING: 6239.F56H11.1c

UniGene: Cel.12816