Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog (CG33276)

中文名稱：

Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog(CG33276)
貨號：

CSB-YP745324DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog(CG33276)
貨號：

CSB-EP745324DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog(CG33276)
貨號：

CSB-EP745324DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog(CG33276)
貨號：

CSB-BP745324DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Drosophila melanogaster Ubiquitin-related modifier 1 homolog(CG33276)
貨號：

CSB-MP745324DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CG33276
Uniprot No.：

Q7KU86
別名：

Urm1; CG33276; Ubiquitin-related modifier 1 homolog
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-101
氨基酸序列

MGTPELKIIL EFSAGAELLF GNIKRRELNL DGKQKWTIAN LLKWMHANIL TERPELFLQG DTVRPGILVL INDTDWELLG ELDYELQPND NVLFISTLHG G
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as Jafrac1, Ciao1, Eip71CD and GILT1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates. Plays a role in the regulation of JNK signaling in response to oxidative stress.
基因功能參考文獻：
1. Loss of Urm1 directly or indirectly results in an activation of the JNK pathway and by extension elevated expression levels of multiple oxidative stress response genes, including Jafrac1 and gstD1. PMID: 26715182
亞細胞定位：

Cytoplasm.
蛋白家族：

URM1 family
數據庫鏈接：

KEGG: dme:Dmel_CG33276

STRING: 7227.FBpp0113022

UniGene: Dm.27886