Recombinant Drosophila melanogaster Protein Wnt-5 (Wnt5), partial

中文名稱：

黑腹果蠅Wnt5重組蛋白
貨號：

CSB-YP340985DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Wnt5重組蛋白
貨號：

CSB-EP340985DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Wnt5重組蛋白
貨號：

CSB-EP340985DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Wnt5重組蛋白
貨號：

CSB-BP340985DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Wnt5重組蛋白
貨號：

CSB-MP340985DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Wnt5
Uniprot No.：

P28466
別名：

Wnt5; Wnt-3; WNT-5; CG6407Protein Wnt-5; dWnt-3; dWnt-5
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May have a role in limb and CNS development; may be a downstream target of Dll that acts in the specification of these primordia.
基因功能參考文獻：
1. The pool of ADP-ribosylated Axin, which is degraded under basal conditions, increases immediately following Wnt stimulation in both Drosophila and human cells. PMID: 27138857
2. Wnt5 promotes dendrite termination on the periphery of sternites through the Ryk receptor family kinase Derailed (Drl) and the Rho GTPase guanine nucleotide exchange factor Trio in C4da neurons PMID: 26302791
3. Wnt5 is required for projection neurons dendrites migration and targeting in the developing antennal lobe. PMID: 25378162
4. WNT5 interacts with doughnut and derailed to mediate muscle attachment site selection PMID: 22403643
5. Wnt5 is broadly expressed in the developing brain and regulates axonal development of mushroom body neurons. PMID: 21451033
6. Derailed keeps axons out of the posterior commissure by acting as a receptor for Wnt5 PMID: 12660735
7. Wnt5 protein is predominantly present on posterior commissural axons and at a low level on the anterior commissure and longitudinal projections PMID: 15282154
8. WNT5 is required intrinsically within mushroom bodies neurons for proper axonal growth and probably interacts with the extrinsic DRL receptor in order to stop axonal growth. PMID: 17652353
9. The wnt5 as an anterograde signal that is expressed by olfactory axons and demonstrate a previously unappreciated, yet powerful, role for glia in patterning the Drosophila olfactory map. PMID: 17934456
10. Wnt5 regulates the growth of the Drosophila neuromuscular junction (NMJ) by signaling through the Derailed receptor. PMID: 17963254
11. Src family kinases play novel roles in WNT5/Derailed-mediated signaling PMID: 18539923
12. Derailed protein (Drl) and derailed protein-2 (Drl-2) play opposing roles in Wnt5 signaling during olfactory system development, depending upon the type of cells in which they are expressed. PMID: 19369566
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Wnt family
組織特異性：

Dynamic expression pattern during embryogenesis. Expression is seen in the limb primordia of the head and thoracic segments, mesodermal and neurogenic regions.
數據庫鏈接：

KEGG: dme:Dmel_CG6407

STRING: 7227.FBpp0074394

UniGene: Dm.5375