Recombinant Drosophila melanogaster Possible lysine-specific histone demethylase 1 (Su (var)3-3), partial

中文名稱(chēng)：

黑腹果蠅Su(var)3-3重組蛋白
貨號(hào)：

CSB-YP894284DLU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

黑腹果蠅Su(var)3-3重組蛋白
貨號(hào)：

CSB-EP894284DLU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

黑腹果蠅Su(var)3-3重組蛋白
貨號(hào)：

CSB-EP894284DLU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

黑腹果蠅Su(var)3-3重組蛋白
貨號(hào)：

CSB-BP894284DLU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

黑腹果蠅Su(var)3-3重組蛋白
貨號(hào)：

CSB-MP894284DLU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Su(var)3-3
Uniprot No.：

Q9VW97
別名：

Su(var)3-3; Hdm; LSD1; CG17149; Possible lysine-specific histone demethylase 1; EC 1.-.-.-
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for heterochromatic gene silencing. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and tri-methylated 'Lys-4' of histone H3. May also demethylate 'Lys-9' of histone H3, Plays a role in the repression of neuronal genes.
基因功能參考文獻(xiàn)：
1. identified lysine-specific demethylase 1 (lsd1) and CoRest as differentiation regulators PMID: 25512561
2. Lsd1 functions to repress decapentaplegic (dpp) expression in adult germaria PMID: 21482791
3. found that the Lysine Specific Demethylase 1 gene (lsd1) was important for the proper cell type-specific development of wing patterning PMID: 21146519
4. Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development. PMID: 17462898
亞細(xì)胞定位：

Nucleus. Chromosome. Note=In early cleavage, protein displays a uniform nuclear distribution. At metaphase, protein is detected at the chromosome periphery, and between the chromosomes during anaphase. A rather uniform interphase chromatin association is detected until syncytial blastoderm. When cellular blastoderm is formed (cycle 14), protein is preferably associated with pericentric heterochromatin situated at the apical pole of blastoderm nuclei. Later in development, protein is only found over euchromatin. In the germline precursor pole cells, protein remains uniformly distributed within the nucleus.
蛋白家族：

Flavin monoamine oxidase family
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG17149

STRING: 7227.FBpp0074594

UniGene: Dm.11528