Recombinant Drosophila melanogaster DNA-binding protein D-ETS-6 (Ets21C)

中文名稱：

黑腹果蠅Ets21C重組蛋白
貨號：

CSB-YP326915DLU
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Ets21C重組蛋白
貨號：

CSB-EP326915DLU
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Ets21C重組蛋白
貨號：

CSB-EP326915DLU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Ets21C重組蛋白
貨號：

CSB-BP326915DLU
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Ets21C重組蛋白
貨號：

CSB-MP326915DLU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ets21C
Uniprot No.：

P29776
別名：

Ets21C; ETS-6; CG2914DNA-binding protein D-ETS-6
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-475
氨基酸序列

MAILQNSRQS HKQLPIISQT IRSAWCQQRP INAMHQDVRQ KSIGSGNETK LEAKETEVPT NRRRRRRRCS SSSTSDSSAS SYSSTDSDSG SSTSSSSIRS QLPALNLPVP LPLATPTPPA VSSPHQAPSP RRNSSDSNRS VSPVEVPVDP HAWTPEDIAS WVRWATRKFK LDPEPDIDRF PKDAQELCDL SRADFWVCAG SRRGGMLLAQ HFAISLYHAT GRETSPMLND DEPNPYQLLN AASHRLVAQG SGGQIQLWQF LLELLADSSN ANAISWEGQS GEFRLIDPDE VARRWGERKA KPNMNYDKLS RALRYYYDKN IMTKVHGKRY AYKFDFHGLM AACQAQAQGG DPASSMLGSY NHHAGGAMQL GRHPPPLHHH PQHSHPHHQL GQPHFLHPHH SSPASNSSSL GFPSSSTASS QASPGQAPAS SSASTSNFTA PFQGGTAGVD PARTSTSSAG NYDQGPVTPT TNAFN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Data show that Ets21C has a crucial role in the regulation of tumor growth as a loss of function critically reduced tumor growth, whereas an excess of Ets21C further increased tumor size. While Ets21C was shown only with a role in fine-tuning the transcriptional program of neoplastic tumors, results point towards a more fundamental role as activator of a specific set of target genes driving tumor growth and invasion. PMID: 27713480
2. malignant transformation of the ras(V12)scrib(1) tumors requires bZIP protein Fos, the ETS-domain factor Ets21c and the nuclear receptor Ftz-F1, all acting downstream of Jun-N-terminal kinase. PMID: 26398940
3. These studies identify Cic, Pnt, and Ets21C as critical downstream effectors of EGFR signaling in Drosophila Intestinal Stem Cells PMID: 26683696
亞細胞定位：

Nucleus.
蛋白家族：

ETS family
組織特異性：

Embryonic ventral nervous system and 1 pair of neurons in each thoracic segment.
數據庫鏈接：

KEGG: dme:Dmel_CG2914

STRING: 7227.FBpp0077739

UniGene: Dm.21518