Recombinant Dog Myc proto-oncogene protein (MYC)

中文名稱：

熟悉的犬MYC重組蛋白
貨號：

CSB-YP634666DO
規格：
來源：

Yeast
其他：

中文名稱：

熟悉的犬MYC重組蛋白
貨號：

CSB-EP634666DO
規格：
來源：

E.coli
其他：

中文名稱：

熟悉的犬MYC重組蛋白
貨號：

CSB-EP634666DO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

熟悉的犬MYC重組蛋白
貨號：

CSB-BP634666DO
規格：
來源：

Baculovirus
其他：

中文名稱：

熟悉的犬MYC重組蛋白
貨號：

CSB-MP634666DO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MYC
Uniprot No.：

Q28350
別名：

MYC; Myc proto-oncogene protein; Proto-oncogene c-Myc; Transcription factor p64
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

full length protein
表達區域：

1-439
氨基酸序列

MPLNVSFANR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVASF SPRGDDDGGG GSFSTADQLE MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKLA SYQAARKDSG SPSPARGPGG CSTSSLYLQD LSAAASECID PSVVFPYPLN DSSSPKPCAS PDSAAFSPSS DSLLSSAESS PRASPEPLAL HEETPPTTSS DSEEEQEDEE EIDVVSVEKR QAPAKRSESG SPSAGGHSKP PHSPLVLKRC HVSTHQHNYA APPSTRKDYP AAKRARLDSG RVLKQISNNR KCASPRSSDT EENDKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT AYILSVQAEE QKLLSEKDLL RKRREQLKHK LEQLRNSGA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release.
基因功能參考文獻：
1. The data presented here suggest that cobalamin deficiency in Shar Peis is not related to any mutations of the MYC_CANFA gene according to the genotyping and sequencing results in this study. PMID: 23278253
2. study shows decorin blocks several biological activities mediated by Met signaling axis; these effects were mediated by downregulation of noncanonical beta-catenin levels; Myc was downregulated by decorin; phosphorylation of Myc at threonine 58 was induced PMID: 20974860
3. Eyelid and third eyelid tumors of dogs express both the p53 and the c-Myc genes as shown by PCR and RT-PCR. PMID: 20447023
亞細胞定位：

Nucleus, nucleoplasm. Nucleus, nucleolus.
數據庫鏈接：

KEGG: cfa:403924

STRING: 9615.ENSCAFP00000001523

UniGene: Cfa.3786