Recombinant Dog Inactive pancreatic lipase-related protein 1 (PNLIPRP1)

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中文名稱：

Recombinant Dog Inactive pancreatic lipase-related protein 1(PNLIPRP1)
貨號：

CSB-EP018263DO
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

PNLIPRP1
Uniprot No.：

P06857
別名：

PNLIPRP1; PLRP1; Inactive pancreatic lipase-related protein 1; PL-RP1
種屬：

Canis lupus familiaris (Dog) (Canis familiaris)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

65.7kDa
表達區域：

18-467aa
氨基酸序列

KEVCYEQIGCFSDAEPWAGTAIRPLKVLPWSPERIGTRFLLYTNKNPNNFQTLLPSDPSTIEASNFQTDKKTRFIIHGFIDKGEENWLLDMCKNMFKVEEVNCICVDWKKGSQTSYTQAANNVRVVGAQVAQMLSMLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEASFQGTPEEVRLDPTDADFVDVIHTDAAPLIPFLGFGTSQQMGHLDFFPNGGEEMPGCKKNALSQIVDLDGIWEGTRDFVACNHLRSYKYYSESILNPDGFASYPCASYRAFESNKCFPCPDQGCPQMGHYADKFAVKTSDETQKYFLNTGDSSNFARWRYGVSITLSGKRATGQAKVALFGSKGNTHQFNIFKGILKPGSTHSNEFDAKLDVGTIEKVKFLWNNNVVNPTFPKVGAAKITVQKGEEKTVHSFCSESTVREDVLLTLTPC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-SUMO-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產品描述：

The process of expressing this Dog PNLIPRP1?recombinant protein in E.coli?expression system requires the following steps: use of competent E. coli cells to take up DNA sequence of interest, the exogenous plasmid is transferred into the cell, and the transcription and translation are directly replicated in the cell, selection of transformed E. coli using a selection marker, expansion of selected E. coli to a higher scale in appropriate culture media, such as classic LB options Growth Systems and lastly isolation and purification.And we finally get a PNLIPRP1 protein with N-terminal 6xHis-SUMO tag?and it is determined by SDS-PAGE with a purity of 90%+.
PNLIPRP1 (PLRP1) is a protein coding gene that encodes Inactive pancreatic lipase-related protein 1. According to some studies, PNLIPRP1 may have the following features.
The loss of PNLIPRP1 and NR1I3 was mainly associated with specific eating habits. The exons of these diabetic patients showed the rs2305205 mutation in the PNLIPRP1 gene and the rs778701848 mutation in the CAMKK2 gene. PNLIPRP1 showed no lipase activity against all known substrates. PNLIPRP1 acts as a negative regulator of pancreatic lipase activity by competing with PL to occupy colonic lipase.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro).
亞細胞定位：

Secreted.
蛋白家族：

AB hydrolase superfamily, Lipase family
組織特異性：

Detected in pancreas (at protein level).
數據庫鏈接：

KEGG: cfa:404010

STRING: 9615.ENSCAFP00000017453

UniGene: Cfa.3881