Recombinant Dog Galactocerebrosidase (GALC), partial

中文名稱：

熟悉的犬GALC重組蛋白
貨號：

CSB-YP009196DO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

熟悉的犬GALC重組蛋白
貨號：

CSB-EP009196DO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

熟悉的犬GALC重組蛋白
貨號：

CSB-EP009196DO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

熟悉的犬GALC重組蛋白
貨號：

CSB-BP009196DO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

熟悉的犬GALC重組蛋白
貨號：

CSB-MP009196DO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

GALC
Uniprot No.：

P54804
別名：

GALC; Galactocerebrosidase; GALCERase; EC 3.2.1.46; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
基因功能參考文獻：
1. This study demonistrated that CNS and PNS disease progression can be quantified over time in the canine model of GLD with tools identical to those used to assess human patients. PMID: 27638585
相關疾病：

Defects in GALC are the cause of globoid cell leukodystrophy (GLD). This deficiency results in the insufficient catabolism of several galactolipids that are important in the production of normal myelin.
亞細胞定位：

Lysosome.
蛋白家族：

Glycosyl hydrolase 59 family
數據庫鏈接：

KEGG: cfa:403916

STRING: 9615.ENSCAFP00000031633

UniGene: Cfa.3777