Recombinant Degenerin unc-8 (unc-8), partial

中文名稱：

秀麗隱桿線蟲unc-8重組蛋白
貨號：

CSB-YP630358CXY
規(guī)格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲unc-8重組蛋白
貨號：

CSB-EP630358CXY
規(guī)格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲unc-8重組蛋白
貨號：

CSB-EP630358CXY-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲unc-8重組蛋白
貨號：

CSB-BP630358CXY
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲unc-8重組蛋白
貨號：

CSB-MP630358CXY
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

unc-8
Uniprot No.：

Q21974
別名：

unc-8; R13A1.4Degenerin unc-8; Uncoordinated protein 8
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻(xiàn)：
1. The authors propose that the depolarizing effect of UNC-8-dependent sodium import elevates intracellular calcium in a positive feedback loop involving the voltage-gated calcium channel UNC-2 and the calcium-activated phosphatase TAX-6/calcineurin to initiate a caspase-dependent mechanism that disassembles the presynaptic apparatus. PMID: 27403890
2. Neurotoxic UNC-8(G387E) and UNC-8(A586T)mutants encode hyperactivated channels blocked by extracellular calcium and magnesium. PMID: 23898007
亞細(xì)胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Amiloride-sensitive sodium channel (TC 1.A.6) family
數(shù)據(jù)庫鏈接：

STRING: 6239.R13A1.4

UniGene: Cel.12253