Recombinant Danio rerio Tyrosine-protein kinase receptor Tie-2 (tie2), partial

中文名稱：

斑馬魚tie2重組蛋白
貨號：

CSB-YP524227DIL
規格：
來源：

Yeast
其他：

中文名稱：

斑馬魚tie2重組蛋白
貨號：

CSB-EP524227DIL
規格：
來源：

E.coli
其他：

中文名稱：

斑馬魚tie2重組蛋白
貨號：

CSB-EP524227DIL-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚tie2重組蛋白
貨號：

CSB-BP524227DIL
規格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚tie2重組蛋白
貨號：

CSB-MP524227DIL
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

tie2
Uniprot No.：

O73791
別名：

tie2; tie-2; Tyrosine-protein kinase receptor Tie-2; EC 2.7.10.1; Tyrosine kinase with Ig and EGF homology domains-2
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Tyrosine-protein kinase that acts as cell-surface receptor for angiopoietins and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Can activate or inhibit angiogenesis, depending on the context. Angiopoietin signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors.
基因功能參考文獻：
1. observations demonstrate that Tie2 is an important regulator of tip cell behaviors PMID: 25001479
亞細胞定位：

Cell membrane; Single-pass type I membrane protein. Cell junction. Cell junction, focal adhesion. Cytoplasm, cytoskeleton.
蛋白家族：

Protein kinase superfamily, Tyr protein kinase family, Tie subfamily
組織特異性：

Expressed in most populations of endothelial cells in 24 hours embryos. Not present in intersegmental vessels.
數據庫鏈接：

KEGG: dre:30747

STRING: 7955.ENSDARP00000055680

UniGene: Dr.75820