Recombinant Danio rerio Serine protease HTRA1A (htra1a)

中文名稱：

斑馬魚htra1a重組蛋白
貨號(hào)：

CSB-YP756952DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

斑馬魚htra1a重組蛋白
貨號(hào)：

CSB-EP756952DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

斑馬魚htra1a重組蛋白
貨號(hào)：

CSB-EP756952DIL-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚htra1a重組蛋白
貨號(hào)：

CSB-BP756952DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚htra1a重組蛋白
貨號(hào)：

CSB-MP756952DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

htra1a
Uniprot No.：

Q6GMI0
別名：

htra1a; htra1; prss11; zgc:92029; Serine protease HTRA1A; EC 3.4.21.-; High-temperature requirement A serine peptidase 1A; Serine protease 11
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

19-479
氨基酸序列

DA RLSKRYVIGG CPSHCDKSMC PTMPKDCSTG QVMDHCNCCL VCASGEGEAC GGVGKLGDPV CGESLECSVT GGVSYSATVR RRGKQGVCVC KSSDPVCGSD GVSYRDICEL KRVSNRAQSL QQPPVLFIQR GACGTSLHDN PNSLRYKYNF IADVVEKIAP AVVHIELYRK MVYSKREMAV ASGSGFVVSD DGLIVTNAHV VANKNRVKVE LKNGASYDAK IKDVDEKADI ALIKIDLPNK LPVLLLGRSA DLRPGEFVVA IGSPFSLQNT VTTGIVSTTQ RGGKELGLRN SDMDYIQTDA IINYGNSGGP LVNLDGEVIG INTLKVTAGI SFAIPSDKIR QFLAESYDRL ARGRGTTKKR YIGVRMMTLT PSLSKELKGR LRDFPDITSG AYVIEVISKT PAAAGGLKEH DVIISINGQR ISTATDVSAI IKKESSLRVV VRRGNEDIIL TIIPMEIDP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. Consequently, may regulate many physiological processes. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.
基因功能參考文獻(xiàn)：
1. HtrA1 is indispensable for dorsoventral patterning in early zebrafish embryogenesis and serves as a key upstream regulator of FGF signaling through the control of FGF levels. PMID: 22949504
亞細(xì)胞定位：

Secreted. Cytoplasm, cytosol.
蛋白家族：

Peptidase S1C family
數(shù)據(jù)庫(kù)鏈接：

KEGG: dre:431766

STRING: 7955.ENSDARP00000048135

UniGene: Dr.82106