Recombinant Danio rerio MAGUK p55 subfamily member 5-A (mpp5a), partial

中文名稱：

斑馬魚mpp5a重組蛋白
貨號：

CSB-YP816939DIL
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

斑馬魚mpp5a重組蛋白
貨號：

CSB-EP816939DIL
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

斑馬魚mpp5a重組蛋白
貨號：

CSB-EP816939DIL-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚mpp5a重組蛋白
貨號：

CSB-BP816939DIL
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚mpp5a重組蛋白
貨號：

CSB-MP816939DIL
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

mpp5a
Uniprot No.：

Q8JHF4
別名：

mpp5a; mpp5; nok; MAGUK p55 subfamily member 5-A; MAGUK family factor; Nagie oko protein
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis. Functions in cellular patterning of the retina.
基因功能參考文獻：
1. This study shows that Spatial-temporal expressions of Nagie oko and their interdependence in zebrafish central nervous system during early development. PMID: 24071007
2. The structural disorganization of the pronephric glomerulus in the mpp5a(m520) mutant is likely to result from circulatory failure, rather than the anomaly of Mpp5a protein in the glomerulus. PMID: 23027442
3. the ratio of the number of cells undergoing neurogenic cell division to the total number of cells undergoing mitosis was decreased in retinas of nagie oko knockout zebrafish. PMID: 20362667
4. morphogenesis of the neural tube requires nok function PMID: 15788456
5. Data show that nagie oko contains a predicted nuclear export and two conserved nuclear localization signals and loss of the predicted nuclear export signal results in nuclear protein accumulation. PMID: 18058913
6. deletion constructs of Nok in functional rescue experiments to define domains essential for cell polarity, maintenance of epithelial integrity and cardiac morphogenesis.Nok does not interact with Crumbs proteins upon deletion of the PDZ domain PMID: 18628301
7. that Nok is required for retinal pigment epithelium integrity in a tissue-autonomous manner PMID: 19074041
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亞細胞定位：

Apical cell membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Localizes to the apical region of the cell membrane, in the vicinity of junctional complexes in the neuroepithelium and the photoreceptor layer. Enriched in the areas immediately apical to the adherens junctions-associated actin bundles.
蛋白家族：

MAGUK family
組織特異性：

Expressed in the retina and in the neural tube.
數據庫鏈接：

KEGG: dre:252845

STRING: 7955.ENSDARP00000078936

UniGene: Dr.18838