Recombinant Danio rerio Achaete-scute homolog 1b (ascl1b)

中文名稱：

Recombinant Danio rerio Achaete-scute homolog 1b(ascl1b)
貨號：

CSB-YP835444DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Danio rerio Achaete-scute homolog 1b(ascl1b)
貨號：

CSB-EP835444DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Danio rerio Achaete-scute homolog 1b(ascl1b)
貨號：

CSB-EP835444DIL-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Danio rerio Achaete-scute homolog 1b(ascl1b)
貨號：

CSB-BP835444DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Danio rerio Achaete-scute homolog 1b(ascl1b)
貨號：

CSB-MP835444DIL
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ascl1b
Uniprot No.：

Q90260
別名：

ascl1b; ash; ashbAchaete-scute homolog 1b; Zash-1b
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

full length protein
表達區(qū)域：

1-195
氨基酸序列

MEATVVATTQ LTQDSFYQPF SESLEKQDRE CKVLKRQRSS SPELLRCKRR LTFNGLGYTI PQQQPMAVAR RNERERNRVK QVNMGFQTLR QHVPNGAANK KMSKVETLRS AVEYIRALQQ LLDEHDAVSA VLQCGVPSPS VSNAYSAGPE SPHSAYSSDE GSYEHLSSEE QELLDFTTWF DRYESGASMA TKDWC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter. Involved in neurogenesis. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. May mediate transcription activation by binding to the E box-containing promoter.
基因功能參考文獻：
1. Data demonstrate that MASH1/Ascl1a is a fundamental regulator of axonal growth across vertebrates and can induce modifications to the intrinsic state of neurons to promote functional regeneration in response to central nervous system injury. PMID: 25751153
2. ascl1b/Ascl1 silencing by valproic acid results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome PMID: 24135485
3. The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 and NEUROG3 is not the unique pancreatic endocrine cell fate determinant in vertebrates. PMID: 23835295
亞細胞定位：

Nucleus.
組織特異性：

In the 24 hours embryo, expressed in hindbrain close to the anterior and posterior boundaries of rhombomeres 2-6 and in ventral cells close to the floor plate of most rhombomeres. Also expressed in the telencephalon, diencephalon, tegmentum and spinal cor
數(shù)據(jù)庫鏈接：

KEGG: dre:30478

STRING: 7955.ENSDARP00000022655

UniGene: Dr.318