Recombinant Cullin-3 (cul-3), partial

中文名稱：

Recombinant Cullin-3(cul-3) ,partial
貨號：

CSB-YP619136CXY
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Cullin-3(cul-3) ,partial
貨號：

CSB-EP619136CXY
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Cullin-3(cul-3) ,partial
貨號：

CSB-EP619136CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Cullin-3(cul-3) ,partial
貨號：

CSB-BP619136CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Cullin-3(cul-3) ,partial
貨號：

CSB-MP619136CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

cul-3
Uniprot No.：

Q17391
別名：

cul-3; Y108G3AL.1Cullin-3; CUL-3
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule stability in the early embryo. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of microtubule severing protein mei-1 downstream of unc-89.
基因功能參考文獻：
1. the identification of a large family of BTB-domain proteins as substrate-specific adaptors for C. elegans CUL-3 PMID: 13679922
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Cullin family
數據庫鏈接：

KEGG: cel:CELE_Y108G3AL.1

STRING: 6239.Y108G3AL.1.2

UniGene: Cel.17033