Recombinant Conus catus Omega-conotoxin CVIB

中文名稱：

Recombinant Conus catus Omega-conotoxin CVIB
貨號：

CSB-YP348411COE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Conus catus Omega-conotoxin CVIB
貨號：

CSB-EP348411COE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Conus catus Omega-conotoxin CVIB
貨號：

CSB-EP348411COE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Conus catus Omega-conotoxin CVIB
貨號：

CSB-BP348411COE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Conus catus Omega-conotoxin CVIB
貨號：

CSB-MP348411COE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

P58918
別名：

Omega-conotoxin CVIB
種屬：

Conus catus (Cat cone)
蛋白長度：

Cytoplasmic domain
表達區域：

1-25
氨基酸序列

CKGKGASCRK TMYDCCRGSC RSGRC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This toxin blocks N-, P- and Q-type calcium channels. It shows high activities on Cav2.1/CACNA1A (IC(50)=11 nM) and Cav2.2/CACNA1B (IC(50)=7.7 nM). In addition, it shows a higher potency when Cav2.2/CACNA1B is only expressed with the ancillary subunit CACNB3 (IC(50)=1.6 nM) than on Cav2.2/CACNA1B expressed with the ancillary subunits CACNA2D1 and CACNB3 (IC(50)=12 nM). Both the Cav2.2/CACNA1B block by this toxin and the recovery are voltage-independent. It is noteworthy that ancillary subunits beta do not modulate recovery from this toxin block, since Cav2.2/CACNA1B expressed with either the ancillary subunit CACNB2a (isoform 2a) or with CACNB3 exhibits moderate recovery.
亞細胞定位：

Secreted.
蛋白家族：

Conotoxin O1 superfamily
組織特異性：

Expressed by the venom duct.