Recombinant Chicken Cofilin-2 (CFL2)

中文名稱：

Recombinant Chicken Cofilin-2(CFL2)
貨號：

CSB-YP005281CH
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Chicken Cofilin-2(CFL2)
貨號：

CSB-EP005281CH
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Chicken Cofilin-2(CFL2)
貨號：

CSB-EP005281CH-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Chicken Cofilin-2(CFL2)
貨號：

CSB-BP005281CH
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Chicken Cofilin-2(CFL2)
貨號：

CSB-MP005281CH
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CFL2
Uniprot No.：

P21566
別名：

CFL2; Cofilin-2; Cofilin; muscle isoform
種屬：

Gallus gallus (Chicken)
蛋白長度：

Full length protein
表達區域：

1-166
氨基酸序列

MASGVTVNDE VIKVFNDMKV RKSSTPEEIK KRKKAVLFCL SDDKKQIIVE EAKQILVGDI GDTVEDPYTA FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
基因功能參考文獻：
1. Study reports chicken cofilactin (cofilin-decorated actin filament) 3.8 A resolution cryo-electron microscopy structure which enables to determine the nature of the cofilin-binding-induced conformational transition in the actin subunit. The cofilin-actin interface consists of three distinct parts and cofilin preferentially binds ADP-F-actin versus ATP-actin. PMID: 29749375
2. Our results suggest that the activity of A3-cofilin and also S3-cofilin can be regulated by PIP(2) in the cytoplasm of muscle cells. PMID: 17823847
亞細胞定位：

Nucleus matrix. Cytoplasm, cytoskeleton.
蛋白家族：

Actin-binding proteins ADF family
組織特異性：

Widely distributed in various tissues.
數據庫鏈接：

KEGG: gga:423320

STRING: 9031.ENSGALP00000016266

UniGene: Gga.19407