Recombinant Cell death abnormality protein 12 (ced-12), partial

中文名稱：

Recombinant Cell death abnormality protein 12(ced-12) ,partial
貨號：

CSB-YP844661CXY
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Cell death abnormality protein 12(ced-12) ,partial
貨號：

CSB-EP844661CXY
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Cell death abnormality protein 12(ced-12) ,partial
貨號：

CSB-EP844661CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Cell death abnormality protein 12(ced-12) ,partial
貨號：

CSB-BP844661CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Cell death abnormality protein 12(ced-12) ,partial
貨號：

CSB-MP844661CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ced-12
Uniprot No.：

Q8STE5
別名：

ced-12; Y106G6E.5Cell death abnormality protein 12
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in programmed apoptosis and necrosis. Required for the cell corpse engulfment process. Has roles in the formation of actin halos and distal tip cell migration. Negatively regulates the unc-6/Netrin receptor unc-5 to control distal tip cell migration along the anterior-posterior axis of the body. Plays no role in amphid axon outgrowth.
基因功能參考文獻：
1. Epistatic analyses place mtm-1 upstream of the ternary GEF complex, which consists of ced-2, ced-5 and ced-12, and parallel to mig-2. PMID: 21490059
2. Rac activation by the ELMO.Dock180 complex at discrete intracellular locations mediated by the N-terminal 330 amino acids of ELMO1 plays a role in cell migration PMID: 14638695
3. findings suggest that PSR-1 is likely an upstream receptor for the signaling pathway containing CED-2, CED-5, CED-10, and CED-12 proteins and plays an important role in recognizing phosphatidylserine during phagocytosis PMID: 14645848
4. the PH domain of ELMO binds the Dock180-Rac complex in trans and stabilizes Rac in the nucleotide-free transition state PMID: 15247908
亞細胞定位：

Cytoplasm.
數據庫鏈接：

STRING: 6239.Y106G6E.5.1

UniGene: Cel.6169